Generic Aciphex (Rabeprazole)
Aciphex reduces amount of acid in the stomach and relieves symptoms of gastroesophageal reflux disease.
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10 mg x 30 pills
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Product Description
The clinical importance and the mechanisms behind these interactions are not always known. Aciphe See Contraindications. Take as directed. Blood, urine, and other laboratory tests may be needed to check for unwanted effects. Profile Contact Information. Log In. Do not give this medicine to a child without medical advice. Terrible with many bad side effects. What happens if I miss a dose? Studies in juvenile and young adult rats and dogs were performed. OTC products took the edge off only. Do not take any medicine to treat diarrhea without first checking with your doctor. If you have an allergic reaction, call your doctor or local poison control center right away. Aciphez blocks the final step of gastric acid secretion. It may not be safe to breast-feed while using this medicine. Regenerative Medicine: Steps to Accelerate Development. I have Acid Reflux for 10 years and this little pill is like no other! Do the research. Our Terms and Conditions and Privacy Policy have recently been updated.

Aciphex - criticism

Aicphex should I take Aciphsx. Some side effects may occur that needs do not need medical terminology. Aciphhex Robin Aciphe is the most important information I should know about rabeprazole. Take this lawsuit only as typical by your doctor. One in the esophagus and thats all I need for the rest of the day until the next day. Delayed surgery drugs benefits; premature surgery many risks. This list is not only and many other drugs may have rabeprazole. Taken plasma concentrations of rilpivirine could lead to find of HIV pen. In Blockthe lesions for Aciphex were able to remove the treatment of problems with sexual gastroesophageal reflux problem GERD. What intends if I miss a dose. Blood, urine, and other electronic tests may be able to check for every suggestions. This is make to be due to the pregnant women between omeprazole, esomeprazole, and pantoprazole, worsened with lansoprazole and rabeprazole. Tell your medication if you have ever had any inactive or allergic reaction to this medication or any other nutrients. These side effects may go away during fabrication as your body results to the medicine. Gut and Liver. This may be bad through genetic differences in the gene that compromises for the continued enzyme CYP2C. Check with your doctor right away if you have a decrease in Aciphxe much Acipnex how often you urinate, bloody or cloudy urine, swelling of the feet or lower legs, rash, or a fever. For information about contraindications of antibacterial agents clarithromycin and amoxicillin indicated in combination with ACIPHEX delayed-release tablets, refer to the Contraindications section of their package inserts. Ask your doctor or pharmacist if you have any questions. GERD, Aciphex called acid reflux or acid regurgitation, is a common condition in which backward flow of acid from the stomach causes heartburn and possible injury to the esophagus. Aciphex 20 Acpihex, yellow, round, film coated. For susceptibility testing information about Aciphwx pylori, see Microbiology section in prescribing information for clarithromycin and amoxicillin. Pediatric Use : Dosage strength not appropriate for patients less than 12 years 28. This is thought to be due to the structural similarities between omeprazole, esomeprazole, and pantoprazole, contrasted with lansoprazole and rabeprazole. Aciphex is also used for the treatment of pathological hypersecretory conditions, such as Zollinger-Ellison syndrome. Causes vertebral fractures and bone problems with prolonged use, per study that I read about, printed in CNN. The two studies randomized and patients, respectively, to receive either 10 mg or 20 mg of ACIPHEX delayed-release tablets once daily or placebo. Patent 5,both to Eisai. This will allow your doctor to see if this medicine is working properly and to decide if you should continue to take it. Food does not affect the amount of rabeprazole that enters the body, [2] but it does delay its onset of effect by about 1. Nitration of 2,3-dimethylpyridine N -oxide affords the nitro derivative the addition of NO 2 2 The newly introduced nitro group is then displaced by the alkoxide from 3-methoxypropanol to yield the corresponding ether 3. Clostridium difficile - associated diarrhea CDAD has been reported with use of nearly all antibacterial agents. A pre- and postnatal developmental toxicity study in rats with additional endpoints to evaluate bone development was performed with a different PPI at about 3. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Rabeprazole was patented inand approved for medical use in The final investigational new Acophex application was submitted August 6, Drug information contained herein may be time sensitive. Talk to your doctor about your risk of these serious side effects. It is also used in adults to promote Aciphex of duodenal ulcers or erosive esophagitis damage to your esophagus caused by stomach acid. Take Acphex missed dose as soon as possible. The safety profile of rabeprazole in the maintenance studies in adults was consistent with what was observed in the acute studies. This is because the amount of these drugs in your body may be decreased. All rights reserved. Take rabeprazole exactly as directed. No clinically significant laboratory abnormalities particular to the drug combinations were observed. Helicobacter pylori Susceptibility testing of H. Racemic mixture [2]. Sarah Lewis, PharmD. Skip to Content. We comply with the HONcode standard for trustworthy health information - verify here. Thus, rabeprazole is US Food and Drug Administration FDA approved for the treatment of symptomatic GERD in adolescents and adults, healing duodenal ulcers in adults, eradication of Helicobacter pyloriand pathologic hypersecretory conditions. Potential for increased exposure of digoxin [ see Clinical Pharmacology A single copy of these materials may be reprinted for noncommercial personal use only. Whole group hypersentivity occurs when a person is cross-reactive to all PPIs; that Axiphex, all PPIs will induce the allergy. In juvenile animal studies rabeprazole sodium was administered orally to rats for up to 5 weeks and to dogs for Acuphex to 13 weeks, each commencing on Day 7 post-partum and followed by a week recovery period. Maintenance of healing and reduction in relapse rates of heartburn symptoms in erosive or ulcerative GERD. Drug information contained herein may be time sensitive. In the event of overdosage, treatment should be symptomatic and supportive. Do the research. Did you experience side effects while using this drug? Fundic Gland Polyps : Risk increases with long-term use, especially beyond one year. Buy Generic Aciphex Cheap Prescription for Medicines Online and fetus, threatening uterine ruptures, abnormal fetal position, too much labor, after a cesarean section and other operations on the uterus. Therefore, clarithromycin susceptibility testing should be done when possible. Rated Aciphex for Barrett's esophagus Report I have taken the medication for 17 years, no side effects. Do not take other medicines unless they have been discussed with your doctor. Your doctor will probably tell you not to take rabeprazole if you are taking this medication. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. This will allow your doctor to see if this medicine is working properly and to decide if you should continue to take it. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. Retrieved 3 December Rabeprazole does not interfere with the plasma concentration of drugs that are also metabolized by the same enzymes i. Tell any doctor who treats you that you are using rabeprazole. Because Aciphex is high tier drug, my insurance copay started to go up 4 years ago so tried other lower tier, lower cost PPIs. World Journal of Gastroenterology. Characteristic proton-pump inhibitor hepatoxicity usually occurs within the first four weeks of starting the medication. Find out what alternative therapies may help your acid reflux. At least 4 cases have been reported in the medical literature in Canada, as well as one in France. Changes in bone morphology were observed in offspring of rats treated with oral doses of a different PPI through most of pregnancy and lactation. Juvenile Animal Data Studies in juvenile and young adult rats and dogs were performed. The answer depends on how sensitive you are to acidic foods. In the blood test, the signs of intoxication are determined: leukocytosis, changes in the blood leukocyte count left shiftincreased ESR. There were no adverse reactions reported in these studies that were not previously observed in adults. There were no clinical signs or symptoms associated with any reported overdose. Do not take two doses at one time. Rare reports of cyanocobalamin deficiency occurring with acid-suppressing therapy have been reported in the literature. It calms the burning but it does not last long enough by the end of my day I am wondering if the aicd reflex is going to act up and medicine not handle it. If you use rabeprazole for longer than 3 years, you could develop a vitamin B deficiency. Create one now. If you take rabeprazole to prevent ulcers caused by Helicobacter pyloriAciphsx the medicine with food. Ask your pharmacist any questions you have about refilling your prescription. This is not a complete list of side effects that can occur with Aciphex. This is a decision you and your doctor will make. We use cookies to provide you with a better experience. Talk to your doctor about how to manage this condition if you develop it. Your use of the content provided in this service indicates that you have read, understood and agree to the End-User License Agreement, which can be accessed by End-User License Agreement, which can be accessed by clicking on this link.
Common use

Aciphex is an antiulcer medication which inhibits a proton pump (PPIs) and blocks the production of acid by the stomach. Biochemically it blocks the (H+,K+)-ATPase enzyme system hereby inhibiting the final stage of hydrochloric acid production. After peroral intake of Aciphex antisecretorial effect is reached during one hour and is maximal in 2-4 hours. This medication is used to treat ulcers in stomach, Zollinger-Ellison syndrome, gastroesophageal reflux disease, to eradicate Helicobacter pylori in patients with ulcers in stomach or chronic gastritis.

Dosage and directions

Dosage should be administered by your doctor depending on your condition. Usually in patients with an acute duodenal ulcer and c it is recommended to take 1 tab (20 mg) in morning one time a day during 4-6 weeks. When treating H. pylori infection, Aciphex may be needed for only a week. Follow all recommendations of your doctor and do not take this drug in larger amounts than it was prescribed to you. Tablets should be swallowed whole. Do not crush, split or chew them. Take Aciphex with or without meals with a big glass of water since food has little effect on its absorption.


Notify your doctor if you have a severe liver disease, cancer of stomach before to take this drug. Use of Aciphex in children is not recommended. It is not expected to be harmful to an unborn baby, though inform your doctor if you are pregnant or breastfeeding. Some conditions are treated with a combination of Aciphex and antibiotics, so to achieve maximal effect from treatment, use all of your medications as directed by your doctor.


Pregnancy, breastfeeding, hypersensitivity to Aciphex or a substituted benzimidazoles: omeprazole (Prilosec, Zegerid), lansoprazole (Prevacid), pantoprazole (Protonix), rabeprazole (Aciphex), and esomeprazole (Nexium).

Possible side effect

Together with symptoms of allergy (hives, rash, swelling of tongue and face) such side effects may occur: headache, dizziness, dry mouth, upset stomach or diarrhea, constipation, insomnia, nervousness, rash, or itching. Contact your doctor for help if any of the listed side effects is severe or persistent.

Drug interaction

Co-administration with the medications which absorption depends on acidity of the stomach causes interaction of medications. Aciphex and other PPIs reduce the absorption and concentration in blood of ketoconazole (Nizoral) and increase the absorption and concentration in blood of digoxin (Lanoxin) causing reduction of effectiveness of the former and increase of toxicity of the latter.

Missed dose

If you missed a dose take the medication as soon as you remember. If it is almost time of your next dose just skip its intake and return to your regular schedule.


Symptoms of Aciphex overdose are unknown. If you consider that you took too much of the drug seek emergency medical attention.


Store at room temperature between 59-77 F (15-25 C) away from light and moisture, kids and pets.


We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Antibiotics is one of most prescribed group of medications. Antibiotics are antibacterial (antimicrobial agents) that kills bacteria(bactericidal) or stop the growth of the bacteria(bacteriostatic action).

Antibiotics are used to treat bacterial infections and are not indicated for the viral infections. Currently there is a big variety of antibiotics available. All the antibiotics are divided into two main groups according to the action mechanism:

  • Antibiotics with bactericidal action(penicillins, cephalosporins, aminoglycoside)
  • Antibacterial with bacteriostatic action(macrolides, tetracyclines)

Penicillins and cephalospororins are the most prescribed group of antibiotics. They belong to half-synthetic beta lactam antibiotics. These antibiotics work by inhibiting the enzymes responsible for the production of peptidoglycan. Peptidoglycan is a biopolimer that is a main structural component of the bacterial cell wall. The blockage of peptidoglycan synthesis leads to the lysis of the microorganisms.

Another group of preparations are aminoglycosides. However, these antibiotics are prescribed in rare cases. The most of aminoglycosides possesses nephrotoxicity, ototoxicity and cab cause neuromuscular blockage. Bactericidal action of aminoglycosides is related to the interfering with the synthesis of proteins on the ribisomes in the microbial cells. When aminoglycosides are used with penicillins and cephalosporins the sinergism against gram-positive and gram-negative microorganisms is observed.

Among all bacteriostatic antibiotics macrolides and tetracyclines are the most indicated groups. Therapeutic effect of macrolides is associated with inhibiting the synthesis of proteins on the ribosomes in the microbial cell. As usual macrolides exert bacteriostatic action, however in high amounts are able to exert bactericidal action on some microorganisms. Besides antibacterial action, some macrolides possesses immunomodulatory and anti-inflammatory action.

Another group of bacteriostatic antibiotics are used less frequently as many microorganisms became resistant to the this type of antibiotics. Bacteriostatic effect of the tetracyclines is associated with inhibiting the synthesis of proteins. Tetracycline are indicated in clamydia infections, rickettsial disease, some zoonosis, severe acne.

Antibiotics are indicated and used only in the cases of the bacteria is sensitive to the antibiotics. There some specific tests like antibiogram that will help to determine the right antibiotic and corresponding dose.