Generic Amoxil (Amoxicillin)
Amoxil
Amoxil is an antibiotic from the penicillin group used to treat infections such as pneumonia, gonorrhea caused by E. coli, salmonella, etc.
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Product Description
The possibility of superinfections with mycotic or bacterial pathogens should be Amoxjl in mind during therapy. This medicine can affect the results of certain medical tests. Since high urine concentrations of amoxicillin may result in false positive reactions when testing for the presence of glucose in urine using Clinitest, Benedict's solution or Fehling's solution, it is recommended that glucose tests based on enzymatic glucose oxidase reactions such as Clinistix or Testape be used. This proportional difference in the amount excreted from the different doses reflects a lack of linearity between doses and extent of absorption, with a levelling off at higher doses of oral amoxicillin. Amoxil has been authorised in the EU via national procedures. Amoxil capsules also contain the inactive ingredients magnesium stearate and purified talc.

Common use
Amoxil is a broad-spectrum antibiotic from aminopenicillin group. Its mechanism of action is anti-bacterial and consists in inhibition of construction of bacteria cell walls sensitive to Amoxicillin. Cell walls serve to protect bacteria from environment and action of Amoxicillin prevents their propagation. Amoxicillin can be effective against H. influenzae, N. gonorrhoea, E. coli, Pneumococci, Streptococci, and certain strains of Staphylococci. Microorganisms producing penicillase are resistible to Amoxicillin. The medication is not active toward mycobacteria, mycoplasmas, genus Rickettsia, fungi, amoeba, plasmodium, viruses and also Pseudomonas aeruginosa and Proteus spp. (excluding P. mirabilis).

Dosage and directions
Take exactly as prescribed by your doctor. Tell your doctor before to take this medication if you are allergic to cephalosporins (Ceclor, Ceftin, Duricef, Keflex), have had asthma, serious liver or kidney impairement, a bleeding or blood clotting disorders, mononucleosis or any type of allergic reaction in history. You may take Amoxillin with or without food. The chewable tablet should be chewed before you swallow it. Swallow Amoxillin capsules whole with a glass of water.

Precautions
This medication diminishes effect of certain contraception drugs. Continue to take this drug even if you feel fine as life circle of bacteria has certain peculiarities. If you stopped to take the drug having not completed the course of treatment it may result in their further propagation and producing of strains resistant to this medication. Do not give this drug to the sick who have similar symptoms as their illness maybe provoked by other type of microorganisms. Antibiotic medicines can cause diarrhea, inform your doctor if you have it. If you breastfeed and take Amoxicillin, the medication may excrete in milk and cause diarrhea in your baby. Warn your doctor if you suffer from asthma.

Contraindications
Allergy to Amoxicillin or to any other penicillin antibiotic.

Possible side effect
Besides allergy (hives, swelling, rash) possible reaction to Amoxicillin may be diarrhea, dizziness, heartburn, insomnia, nausea, itching, vomiting, confusion, abdominal pain, easy bruising.

Drug interaction
Amoxicillin is not known to decrease effect of birth control pills, increases absorption of digoxin, increases toxicity of metotrexat. Excretion of Amoxicillin by kidneys is slowed by aspirin.

Missed dose
Never take a double dose of this medication. If it is almost time of the next dose just skip the missed portion and continue to take the medicine according to the schedule.

Overdose
Symptoms of Amoxicillin overdose may be vomiting, nausea, diarrhea, disorders of water and electrolytes balance. Contact your doctor for help.


Storage
Store at room temperature between 59 and 86F (15-30C) away from light and moisture.

Disclaimer
We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care advisor or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Antibiotics

Antibiotics is one of most prescribed group of medications. Antibiotics are antibacterial (antimicrobial agents) that kills bacteria(bactericidal) or stop the growth of the bacteria(bacteriostatic action).

Antibiotics are used to treat bacterial infections and are not indicated for the viral infections. Currently there is a big variety of antibiotics available. All the antibiotics are divided into two main groups according to the action mechanism:

  • Antibiotics with bactericidal action(penicillins, cephalosporins, aminoglycoside)
  • Antibacterial with bacteriostatic action(macrolides, tetracyclines)

Penicillins and cephalospororins are the most prescribed group of antibiotics. They belong to half-synthetic beta lactam antibiotics. These antibiotics work by inhibiting the enzymes responsible for the production of peptidoglycan. Peptidoglycan is a biopolimer that is a main structural component of the bacterial cell wall. The blockage of peptidoglycan synthesis leads to the lysis of the microorganisms.

Another group of preparations are aminoglycosides. However, these antibiotics are prescribed in rare cases. The most of aminoglycosides possesses nephrotoxicity, ototoxicity and cab cause neuromuscular blockage. Bactericidal action of aminoglycosides is related to the interfering with the synthesis of proteins on the ribisomes in the microbial cells. When aminoglycosides are used with penicillins and cephalosporins the sinergism against gram-positive and gram-negative microorganisms is observed.

Among all bacteriostatic antibiotics macrolides and tetracyclines are the most indicated groups. Therapeutic effect of macrolides is associated with inhibiting the synthesis of proteins on the ribosomes in the microbial cell. As usual macrolides exert bacteriostatic action, however in high amounts are able to exert bactericidal action on some microorganisms. Besides antibacterial action, some macrolides possesses immunomodulatory and anti-inflammatory action.

Another group of bacteriostatic antibiotics are used less frequently as many microorganisms became resistant to the this type of antibiotics. Bacteriostatic effect of the tetracyclines is associated with inhibiting the synthesis of proteins. Tetracycline are indicated in clamydia infections, rickettsial disease, some zoonosis, severe acne.

Antibiotics are indicated and used only in the cases of the bacteria is sensitive to the antibiotics. There some specific tests like antibiogram that will help to determine the right antibiotic and corresponding dose.