Minocycline is a tetracycline antibiotic indicated to treat urinary tract infections, acne and chlamydia. |
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Product Description
Journal List Br J Pharmacol v. Therapy should be continued for at least 24 to 48 hours after symptoms and fever have subsided. Activation of proteinase-activated receptor-2 by human kallikrein-related Monomycin. Click here for help about this. The effect does not seem to be dose-dependent because the patients on high doses did not do worse than those on the low doses. The evaluation in ex vivo heart systems and cultured cardiac myocytes revealed minocycline's ability to affect apoptotic cell pathways Scarabelli et al. Efficacy of minocycline in patients with amyotrophic lateral sclerosis: a phase III randomised trial. How long does it take to work? Mol Brain. Inflammatory gene expression in cerebral ischemia and trauma. Minocycline is not beneficial Monomycin a phenotypic mouse model MMinomycin Huntington's disease. Kenei Pharmaceutical Co,Ltd. Should tetracycline treatment be used more extensively for rheumatoid arthritis? Therefore, of all the neurological conditions considered here, it appears that minocycline has the most potential in the treatment of multiple sclerosis. Tell your doctor if you notice anything else that is making you feel unwell, even if it is not on this list. Novartis Pharma K. Hear Res. Learn why stress acne is a myth. Anticancer Drugs. Lactose, microcrystalline cellulose, sodium starch glycollate, povidone, sorbitol, magnesium stearate, stearic acid, opadry orange YS-1R Symptoms may include: Minomyciin rash, fever, swollen glands, flu-like symptoms, muscle aches, severe weakness, unusual bruising, or yellowing of your Minoomycin or eyes. Mlnomycin cells that are shed from the lining of the hair follicle become trapped in sebum forming a plug below the surface of the skin, clogging the pores, Minomycib then attracts bacteria, so that the clogged pores become infected and inflamed, which is how the pimples, whiteheads and blackheads comedones of acne form, causing an acne outbreak. May include nausea, vomiting, abdominal pain, hypotension, lethargy, coma, acidosis and azotaemia without a concomitant rise in creatinine. Effects of minocycline on ischaemia Minocycline's ability to limit tissue damage in the kidney, heart, lung and neural cells in the setting of ischaemia both in vitro and in vivo has been documented Yong et al. This is not a complete list of all possible side effects. National Center for Biotechnology InformationU. Minocycline was also effective in combination with atorvastatin, a statin previously reported to be effective in attenuating clinical EAE in mice Youssef et al. Ask your doctor if you have any questions about why it has been prescribed for you. Minocycline also suppressed the type IV collagenolytic activity of these cells, which can contribute to the suppression of their metastatic potential Masumori et al. In venereal diseases when coexistent syphilis is suspected, darkfield examination should be done before treatment is started and the blood serology repeated monthly for at least four months. Conditions that Minomycin capsules mg are used for include: skin infections like severe acne, where bacterial infection has developed; impetigo a superficial skin infection common in young children ; folliculitis infection of the hair root ; furunculosis, boils ; respiratory infections like bronchitis and pneumonia ; genitourinary tract infections like cystitis, prostatitis and gonococcal urethritis ; ear, nose and throat infections like otitis media, sinusitis, tonsillitis, pharyngitis ; eye infections and infected wounds; also to prevent the development of symptoms in meningitis carriers. Other forms include condoms, a diaphragm, or contraceptive foam or jelly. Journal of the American Academy of Dermatology. Despite a moderately high pretreatment relapse rate in the patient group prior to treatment 1. Occasionally, minocycline therapy may result in autoimmune disorders such as drug-related lupus and autoimmune hepatitis, which usually occurs in men who also developed minocycline-induced lupus; however, women are more likely to develop minocycline-induced lupus. The attenuation of neuropathic pain behaviour and motor recovery correlated with reductions in microglia and astrocyte activation respectively. Concomitant treatment of tetracyclines and vitamin A or retinoids is therefore contraindicated. Effects of minocycline on periodontal disease The pharmacological profile of tetracyclines, which combines anti-microbial with anti-inflammatory and anti-apoptotic properties, makes them suitable Minomyciin periodontal disease treatment, which is characterized by an inflammatory process in addition to its well-known microbial aetiology Soory, Inhibitory effect of Minomycib on in vitro invasion and experimental metastasis of mouse renal adenocarcinoma. Minocycline's ability to mitigate cytokine expression in the brain during systemic inflammatory events may be useful in preventing cognitive and behavioural deficits. Altered gene expression in brain ischemia. Neuroprotection by tetracyclines. Allergic reaction such as skin rash, itching, swelling of the lips, face, and mouth or difficulty breathing. Nicotinamide Ibuprofen Aspirin Red light therapy. It is a yellow crystalline powder which is soluble in water. Skip to main content. Tetracyclines also accumulate in the growing skeleton. EA Pharma Co. Reduced efficacy and increased incidence of breakthrough bleeding has been suggested with concomitant use of tetracycline and oral contraceptive preparations. The reduction of atherosclerotic plaque size after minocycline treatment, mainly due to its anti-proliferative effects on VSMCs, suggests a potential application of minocycline on vascular complications. To do so may increase the chance of side effects. Takeda Pharmaceutical Company Limited. Further Information.
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All medicines can have side effects. Altered gene expression in brain ischemia. Minocycline hydrochloride. Preliminary observations and a proposed new mechanism of action. Minocycline was patented in and came into commercial use in It is also used to treat various other infections.
Common use
Minocycline is a tetracycline antibiotic which mechanism of action consists in inhibition of bacterial protein synthesis. Minocycline is used to treat acne, actinomycosis, bacterial infection, bullous Pemphigoid, meningitis, meningococcal pemphigoid, pemphigus, rheumatoid arthritis, rosacea, skin and structure infection, skin infection, gonorrhea, and chlamydiosis.
Dosage and directions
This medication is taken with or without food with a big glass of water. Avoid taking Minomycin with dairy products. Take exactly as prescribed, never exceed your dose or take the medication longer than it was recommended by your doctor. Do not crush, chew or break an extended-release pill. If it is a liquid suspension shake it before use and measure with a special dose measuring spoon.
Precautions
This medication is not recommended in patients with pregnancy, breastfeeding, children younger than 8 y.o. (long use may cause permanent color change of teeth). Avoid long exposure of your body to UV radiation. Avoid taking of iron supplements, multivitamin pills, calcium supplements, antacids, or laxatives at the same time as Minomycin, take these medications two ours before or after Minomycin intake. If you need to do work associated with high concentration of attention (driving) be especially careful.
Contraindications
Hypersensitivity to Minomycin and other tetracycline antibiotics.
Possible side effect
Following side effects may occur while using this medication: hives, rash, swelling of face and tongue, trouble swallowing, severe headache, dizziness, blurred vision, fever, chills, body aches, severe blistering, peeling, urinating less than usual or not at all, pale or yellowed skin, dark colored urine, confusion or weakness, severe pain in your upper stomach, nausea and vomiting, fast heart rate, jaundice, easy bruising or bleeding.
Drug interaction
It is advisable to avoid giving tetracycline-class drugs in conjunction with penicillin. They may also depress plasma prothrombin so adjustment of Minomycin dose administered together with anticoagulant therapy is needed. Absorption of tetracyclines and Minomycin in particular is impaired by antacids containing aluminum, calcium or magnesium, and iron-containing preparations. The concurrent use of tetracycline and methoxyflurane may result in fatal renal toxicity. Minomycin interacts with certain birth control pills and may make it less effective.
Missed dose
If you missed a dose take it when remember. If it almost time of your next dose just skip it and return to your regular schedule. Never take a double dose of this medication.
Overdose
In case of serious and persistent symptoms of nausea, vomiting, and diarrhea consult your doctor about medical attention.
Storage
Store at room temperature between 59-77 F (15-25 C) away from sunlight and moisture, kids and pets. Do not use after expiration term.
Disclaimer
We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.