Generic Noroxin (Norfloxacin)
Noroxin, a fluoroquinolone antibiotic, is used in patients who get frequent urinary tract infections.
Per Pills
400 mg x 30 pills
400 mg x 60 pills
400 mg x 90 pills
400 mg x 120 pills
400 mg x 180 pills
400 mg x 360 pills
Product Description
Complete recovery is expected after stopping the drug and recovery is usually rapid 2 to 8 weeks. For the most part these have been mild. Antibiotics Tendon problems may manifest long after therapy had been completed and in severe cases may result in lifelong disabilities. The standardised quality control procedure requires use of control organisms. Based on urinary concentrations of norfloxacin achieved in humans, breakpoint criteria have been established as listed in Table 3. Norfloxacin is not generally active against obligate anaerobes. The easiest oNroxin to lookup drug information, identify pills, check interactions and set up your own personal medication records. Other brands: Noroxin. In the Federal Register of October 4, Sometimes they are serious, most of the time they are not. Mayo Clinic Marketplace Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. Registration-no: Norfloxacin For more information on this medication choose from the list of selections below. Most commonly the side effects are minor, however some can be more serious. In, Zimmerman HJ. The recommended first line empirical treatment for an uncomplicated lower UTI is trimethoprim, with nitrofurantoin an alternative choice. Norfloxacin stopped. Autoantibodies are usually not present. The length of treatment depends on the problem. All rights reserved. Noroxin Overdose Back to Top. Take this medicine only as directed by your doctor. Review Norfloxacin: a new targeted fluoroquinolone antimicrobial agent. How was your experience with Noroxin? How well did Noroxin work for you? In contrast, DNA gyrases are not present in human [and other eukarotic] cells and the equivalent topoisomerases are not sensitive to fluoroquinolone inhibition. Noroxin Usage Back to Top. If the headaches continue, let your doctor know. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. Any patient that has received a prescription for norfloxacin for a Noroin, in a time frame to be determined as below, is eligible for this audit. Norkxin much to take Take Noroxkn only when prescribed by your doctor. These medicines may be affected by norfloxacin or may affect how well it works. Norfloxacin should be taken at least 1 hour before or 2 hours after a meal, milk, or other dairy products. All medicines can have side effects. Clinical trials. Noroxin Images. Do not take any diarrhoea medicine without first checking with your doctor. You should drink plenty of water or fluids while taking Noroxin. J Korean Med Sci. Click Here. Norfloxacin tablets should be taken 1 hour before or 2 hours after a meal with a glass of water. Haemolytic reactions. These may be serious side effects. Shigellosis, traveller's diarrhoea. In Nroxin patients, careful monitoring of blood glucose is recommended. Elevated serum Niroxin of cyclosporin have been reported with concomitant use with norfloxacin. The interference with the metabolism of caffeine may lead to the reduced clearance of caffeine and a prolongation of its serum half-life, resulting in a caffeine overdose. In the Federal Register of October 4, Convulsions have been reported rarely in patients receiving norfloxacin. Noroxln Images. Ann Hepatol. The Noroxln way to lookup Noroin information, identify pills, check interactions and set up your own personal medication records. See also: Norfloxacin side effects in more detail. Speak with your doctor as soon as possible if you experience the following:. Norfloxacin can Noroxni have serious effects on your nerves, and may cause permanent nerve damage. Call your healthcare provider for medical advice about side effects. Trimethoprim, nitrofurantoin and Noroxon have a narrow range of indications for prescribing, and are predominantly used in the treatment of UTIs. Take this medicine with a full glass of water 8 ounces. Initially, quizzes are posted out with journals and GPs are invited to submit their answers for CME credits. Following the completion of the first cycle, it is recommended that the doctor completes the first part of the Audit of Medical Practice summary sheet Appendix 1. Norfloxacin has been reported to rapidly cross the blood-placenta and blood-milk barrier, and is extensively distributed into the fetal tissues. Norfloxacin may impair your alertness, so make sure your reactions are normal before you drive and before you use tools or machines. Nov—Dec Tendon rupture or swelling of the tendon tendinitis. The recommended first line empirical treatment for an uncomplicated lower UTI is trimethoprim, with nitrofurantoin an alternative choice. In spite of the substantial increase in antibacterial activity of norfloxacin relative to early fluoroquinolones, it did not become a widely used antibiotic. Take the container with you, even if it is empty. These medicines may Noroxih norfloxacin from working properly. Read our full disclaimer. If you do not understand the instructions on the label, ask your doctor or NNoroxin for help. Noroxin well-controlled studies have been done in humans. Outcome and Management The severity of liver injury caused by norfloxacin ranges from mild and transient serum enzyme elevations to self-limited but severe hepatitis, to acute liver failure and death. Ask your doctor if you have any questions about why norfloxacin has been prescribed for you. Norfloxacin was stopped and he improved without further intervention over the next several weeks. Other Requirements Back to Top. Retrieved March 24, See also: Norfloxacin drug interactions in more detail. This medicine helps to control your condition but Norroxin not cure it. Fathers to be: What to pack for hospital. Clostridium difficile -associated diarrhea may occur in connection with the use of any antibacterial drug, especially those with a broad spectrum of activity such as clindamycin, cephalosporins, and fluoroquinolones. It may Noroxinn necessary to stop Noroxin, but do not do so without first talking with your health care professional. The urinary pH may affect the solubility of norfloxacin. Do not be alarmed by this list of possible side effects. If you take the tablets out of the pack, they may not keep well. Avoid caffeine while you are taking norfloxacin, because the medication can make the effects of caffeine stronger. Your antibiotic medicine may need to be changed. Norfloxacin can cause bacteria, which are normally present in the bowel and normally harmless, to multiply and therefore cause the above symptoms. Photosensitivity, Stevens-Johnson syndrome, toxic epidermal necrolysis, exfoliative dermatitis, erythema multiforme, pruritus and leukocytoclastic vasculitis. Norfloxacin has been restricted in the Republic of Ireland due to the risks of C. Fluoroquinoline administration may be associated with the acquisition and outgrowth of a particularly virulent Clostridium strain. Do not take norfloxacin at the same time as taking iron or zinc supplements or multivitamins containing themantacids, sucralfate or didanosine ddI. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records.
Common use

Noroxin is quinolone antibiotic used in treatment of urinary tract such as pyelonephritis, cystitis, urethritis), genitals (prostatitis, cervicitis, endometritis), gastrointestinal tract (salmonellosis, shigellosis), uncomplicated gonorrhea. Mechanism of its action consists in inhibition of DNA gyrase leading to destabilization of the bacterial DNA and death of the susceptible bacteria. Noroxin is active against Staphylococcus spp. (including Staphylococcus aureus), Neisseria spp., E. coli, Citrobacter spp., Klebsiella spp., Proteus spp., Salmonella spp., Enterobacter spp., Hafnia, Shigella spp., Mycobacterium tuberculosis, Vibrio cholerae, Haemophilus influenzae, Chlamydia spp., Mycoplasma spp., And some others. Medication is active for 12 hours.

Dosage and directions

To treat infections of urinary tract take 400 mg of Noroxin two times a day during 7-10 days, to treat non-complicated cystitis treatment continues 3-7 days, and in patents with recurrent chronic infection of urinary tract does up to 12 weeks. For prostatitis the recommended daily dose is 800 mg, divided into 2 doses, for four weeks. Usual single recommended dose to treat gonorrhea is 800 milligrams for 1 day. The maximal daily dose is 800 milligrams. Take with a full glass of water two hours after a meal or one hour before it. Drink plenty of water while taking Noroxin to avoid formation of needle-shaped crystals in your urine. The elderly and people with kidney problems may need to use a reduced dosage or have their kidney function monitored. Take exactly as prescribed by your doctor. Do not start or stop treatment without your doctor's permission.


In elderly and patients with kidney impairment kidney function monitoring is required on a regular basis. This medication may cause photosensibilization, avoid direct sun rays during treatment. Limit consummation of alcoholic beverages as they may worsen such side effects as dizziness, drowsiness and others which may affect your ability to operate machinery and driving.


This medication cannot be administered in patients with hypersensitivity to Noroxin, pregnant and breastfeeding women, children under 18 y.o., individuals with glucose-6-phosphate dehydrogenase deficiency. Caution is required when Noroxin is administered in individuals with cerebral arteriosclerosis, cerebrovascular dysfunctions, epilepsy, epileptic syndrome, Myasthenia gravis, kidney or liver failure.

Possible side effect

The most common side effects include: weakness, headache, drowsiness, dizziness, nausea, stomach upset. Rare but serious side effects are: tremor and sun sensitivity, seizures, mental/mood changes, sore throat/fever, vision changes, hearing loss, change in amount or appearance of urine, jaundice, fainting, changes in heartbeat, easy bruising or bleeding, numbness or tingling of extremities. Tendon damage and weakening of muscles is rare but possible. Stop exercising and claim prompt medical attention if you experience pain in your joint or tendon. In case of pseudomembranous colitis (persistent diarrhea, abdominal or stomach pain/cramping, blood/mucus in your stool) which may develop even a few weeks after the treatment was discontinued, do not use anti-diarrhea products or narcotic pain medications. Tell your doctor immediately about your condition. Prolonged or repeated used of Noroxin may cause oral thrush or a new vaginal yeast infection which symptoms are: white patches in the mouth, a change in vaginal discharge. Inform your doctor immediately if experience allergic reaction (severe dizziness, rash, itching, swelling, trouble breathing).

Drug interaction

Theophylline dose should be decreased while on Noroxin. Noroxin increases the blood concentration of indirect anticoagulants, cyclosporine, decreases effects of nitrofurans. Antacids which contain ions of Al and Mg, medications which contain Fe, Zn2+, sucralfate should be taken at least with four hour interval with Noroxin. Concomitant intake with the medicines decreasing epileptic threshold may lead to epileptic attacks. Dangerous sudden drop in blood pressure or changes in heart rhythm are possible when Noroxin is concomitantly used with the drugs for blood pressure or affecting the heart rhythm. Inform your doctor about all prescribed and over-the-counter medications and herbal products you are taking.

Missed dose

If you miss a dose, take it as soon as you remember unless it is almost time of your next dose. If it is near the time of the next dose, skip the missed dose and return dosing schedule. Do not double the dose to make up the missed dose.


Symptoms of overdose include: dizziness, nausea, vomiting, drowsiness, "cold" sweating, puffy face without major changes in hemodynamic indices.


Store at room temperature in a tight container, away from moisture and humidity.


We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Antibiotics is one of most prescribed group of medications. Antibiotics are antibacterial (antimicrobial agents) that kills bacteria(bactericidal) or stop the growth of the bacteria(bacteriostatic action).

Antibiotics are used to treat bacterial infections and are not indicated for the viral infections. Currently there is a big variety of antibiotics available. All the antibiotics are divided into two main groups according to the action mechanism:

  • Antibiotics with bactericidal action(penicillins, cephalosporins, aminoglycoside)
  • Antibacterial with bacteriostatic action(macrolides, tetracyclines)

Penicillins and cephalospororins are the most prescribed group of antibiotics. They belong to half-synthetic beta lactam antibiotics. These antibiotics work by inhibiting the enzymes responsible for the production of peptidoglycan. Peptidoglycan is a biopolimer that is a main structural component of the bacterial cell wall. The blockage of peptidoglycan synthesis leads to the lysis of the microorganisms.

Another group of preparations are aminoglycosides. However, these antibiotics are prescribed in rare cases. The most of aminoglycosides possesses nephrotoxicity, ototoxicity and cab cause neuromuscular blockage. Bactericidal action of aminoglycosides is related to the interfering with the synthesis of proteins on the ribisomes in the microbial cells. When aminoglycosides are used with penicillins and cephalosporins the sinergism against gram-positive and gram-negative microorganisms is observed.

Among all bacteriostatic antibiotics macrolides and tetracyclines are the most indicated groups. Therapeutic effect of macrolides is associated with inhibiting the synthesis of proteins on the ribosomes in the microbial cell. As usual macrolides exert bacteriostatic action, however in high amounts are able to exert bactericidal action on some microorganisms. Besides antibacterial action, some macrolides possesses immunomodulatory and anti-inflammatory action.

Another group of bacteriostatic antibiotics are used less frequently as many microorganisms became resistant to the this type of antibiotics. Bacteriostatic effect of the tetracyclines is associated with inhibiting the synthesis of proteins. Tetracycline are indicated in clamydia infections, rickettsial disease, some zoonosis, severe acne.

Antibiotics are indicated and used only in the cases of the bacteria is sensitive to the antibiotics. There some specific tests like antibiogram that will help to determine the right antibiotic and corresponding dose.