Generic Toprol Xl (Metoprolol)
Toprol Xl
Toprol Xl is a beta-blocker used to treat high blood pressure, heart pain, abnormal rhythms of the heart.
Per Pills
25 mg x 30 pills
25 mg x 60 pills
25 mg x 90 pills
Per Pills
50 mg x 30 pills
50 mg x 60 pills
50 mg x 90 pills
Per Pills
100 mg x 30 pills
100 mg x 60 pills
100 mg x 90 pills
Product Description
This tablet can be divided into equal doses. Taking it at the same time each day will have the best effect. It is in a class of drugs called beta blockers. Indomethacin, barbiturates, rifampin may decrease effectiveness. Metoprolol contains a stereocenter and consists of two enantiomers. The dose is then usually doubled every second week up to a maximum dose of mg once daily or to the highest tolerated dose. Archived from the original on 12 March This reduction in risk was further Toprol in the subgroup of cardiac resynchronization therapy with implantable cardioverter-defibrillator CRT-D patients HR: 0. The figure below illustrates principal results for a wide variety of subgroup comparisons, including US vs. If there is a need to discontinue treatment with Toprol-XL, this should be done gradually over at least two weeks with the dose reduced by half in each step, down to a final dose of half a Consequently, no reduction in dosage is usually needed in patients with chronic renal failure. Diabetic patients receiving Toprol-XL should be monitored to ensure diabetes control is maintained. Initially 25—mg once daily, alone or with a diuretic. General use of beta-blockers and adherence in this study was high, and a clear dose-dependent relationship was found in carvedilol, but not in metoprolol. Tinnitus, taste disturbances. When adrenaline is blocked in your system, your heart beats more slowly and with less force. Talk to your doctor if you have concerns about the medications that you are being prescribed, or if you start to experience any side effects from them, including Toprol. The maximum dose is Topro mg. This medicine may cause changes in blood sugar levels Toprol cover up signs of low blood sugar, such as a rapid pulse Toprl. These side Topdol may go away during treatment as your body adjusts to the medicine. Laura Cable, Pharm. Topro two brand-name forms of metoprolol as well as the different generic forms are different versions of the medication. If you have Topeol stable and have good results Tporol metoprolol and your Tlprol have been in the normal range, then you can remain on this medication while under the supervision of you health care provider. In case excess hypotension develops, the calcium antagonist should be stopped or the dosage reduced. Tell your doctor if you notice any of the following and they worry you: headache, tiredness, drowsiness, weakness, or lack of energy aches and pains, painful joints nausea feeling sickvomiting stomach upset, diarrhoea or constipation, weight gain dry mouth, changes in taste sensation difficulty sleeping, nightmares mood changes confusion, short-term memory loss, inability to concentrate increased sweating, runny or blocked nose hair loss These side effects are usually mild. Because metoprolol reduces blood pressure, you may get even less blood to these parts of your body. Avoid initiation of a high-dose regimen of extended-release metoprolol in patients undergoing non-cardiac surgery, since such use in patients with cardiovascular risk factors has been associated with bradycardia, hypotension, stroke and death. Reported side effects include dizziness, fatigue, headache, stomach upset, hypotension blood pressure that is lowand vivid dreams or nightmares. Untreated phaeochromocytoma see Section 4. Curley, PharmD. Adults: The usual initial dosage is 25 to mg daily in a single dose. Press Coverage. Retrieved 24 September After rapid disintegration within the gastrointestinal tract, metoprolol is continuously released for approximately 20 hours, and a stable metoprolol plasma concentration is achieved over a dosage interval of 24 hours. If you are taking two doses, after breakfast and after dinner is best, but the closer you can get to 12 hours apart, the better. A: Toprol XL metoprolol succinate is a beta-1 selective adrenergic receptor blocker used To;rol the treatment of hypertension high blood pressure. Keep from freezing. Your physician may recommend lifestyle changes such as moderate exercise along with a diet of mostly oTprol, whole grains, and fruits for better blood pressure Tooprol and health outcomes. Toprol treats high blood pressure and other heart conditions. The mean Toproll Toprol follow-up was one year. A: Metoprolol is a medication that is used to treat various conditions of the heart and blood vessels such as high blood pressure, congestive heart failure and angina among others. I had a little chest pain getting adjusted to it, but now I am okay. Other studies and analyses have suggested that there are differences between the two beta-blockers, say Ruwald and colleagues. Clinical pharmacology studies have confirmed the beta-blocking activity of metoprolol in man, as shown by 1 reduction in heart rate and cardiac output at rest and upon exercise, 2 reduction of systolic blood pressure upon exercise, 3 inhibition of isoproterenol-induced tachycardia, and 4 reduction of reflex orthostatic tachycardia. Jennifer Carey, PharmD. It is possible that your doctor can switch you to a different blood pressure medication if you are having unwanted side effects from metoprolol. Blog at WordPress. Also, are high doses of vitamin D safe? How low can my heart rate get before I should be concerned? The most common side effects with metoprolol are low blood pressure, low heart rate, dizziness and fatigue. I can't stand such cold hands! Inform MD Back to Top. There are no reports of metoprolol causing the blood sugar to rise in the blood. I take it for high blood pressure. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Long-term studies in animals have been conducted to evaluate the carcinogenic potential of metoprolol tartrate. A: Yes, hair loss also called alopecia has been reported as a side effect of metoprolol Lopressorwhich is used to treat several diseases of the cardiovascular system, especially hypertension. A: There are no serious interactions between metoprolol and fish oil. Hematologic: Agranulocytosis, nonthrombocytopenic purpura, thrombocytopenic purpura. It is not known whether metoprolol succinate will harm an unborn baby. You can also take advantage of our free coupon for Toprol XL, which can discount the cost at local pharmacies and can even be used more than once.

That: Toprol

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Hypertension The mechanism of the antihypertensive effects of beta-blocking agents is not fully known. The beta-blockers metoprolol tartrate and Topdol succinate sound alike and treat some of the same conditions, Toprol they're different drugs. This contrasts with the effect of nonselective beta-blockers, Toprpl completely reverse the vasodilating effects of epinephrine. Medications can interact with certain foods. Common side effects include fatigue, tiredness, and shortness of breath. Find the lowest Price. Like this: Like Loading Toprol Precautions Back to Top. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. A black box warning alerts doctors and patients about drug effects that may be dangerous. Did you know prices at pharmacies can change depending on your location? This list is not complete and many other drugs may interact with metoprolol succinate. A doctor may still prescribe it, but with careful monitoring. Toprol-XL is also used to lower your risk of death or needing to be hospitalized for Toprol failure. Leave a Reply Cancel Tlprol Enter your comment here Mayo Clinic does not endorse any of the third party products and services advertised. The main clinical signs of overdosage are Torpol and in some cases decompensation may be rapid. Log in. Kelly, a spokesman for the F. Ralph Neas, the president of the Generic Pharmaceutical Association, the industry trade group, said the F. It will also help you remember when to take it. In extreme cases, serious heart and lung problems may occur. This section does not cite any sources. Liver enzyme effects. After rapid disintegration within the gastrointestinal tract, metoprolol is continuously released for approximately 20 hours, and a stable metoprolol plasma concentration is achieved over a dosage interval of 24 hours. During the late stages of pregnancy these drugs should only be given after weighing the needs of the mother against the risk to the foetus. Geneva: World Health Organization. Swallow the half-tablet whole, without chewing or crushing. Research shows that in addition to medications, diet and exercise can significantly reduce blood pressure. What Is Metoprolol Lopressor? Get emergency medical help if you are having Topro, symptoms. You are commenting using your Google account. Extended release metoprolol Toprol XL is more expensive than immediate release metoprolol Lopressor. Mayo Clinic does not endorse any of the third party products and services advertised. Toproll your doctor or pharmacist for more information. The recommended dose range for Toprol for treating hypertension in children 6 years of age or older is 0. It is not advisable to suddenly stop taking metoprolol as this may worsen the medical condition for which it was prescribed. In fact, sources report that metoprolol may mask the symptoms of low blood sugar. They come as the F. Q: I have a problem with hair thinning. Some of the more common side effects of metoprolol are fatigue, dizziness, diarrhea, itching, rash, depression, and slow heartbeat. Adults In man, absorption of metoprolol is rapid and complete. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. Metoprolol belongs to the group of drugs called beta-blockers.
Common use

Toprol acts mostly blocking beta-adrenoreceptors of the heart and is used to treat hypertension, chest pain (angina), abnormal rhythms of the heart, to treat and prevent myocardial infarction. This medication influences autonomic nervous system which stipulates increased heart rate by blocking its receptors and thus reducing abnormally rapid heart rhythms. It also diminishes myocard irritability, cardiac output and causes other effects.

Dosage and direction

This medication should be taken with food or just after a meal. Do not chew, squash or break a tablet, drink a glass of water with it. Dosage depends on the treated disease and may vary between 100-450 mg daily. Your individual dosage should be prescribed by your physician. Aged patients are recommended to start from 50 mg daily dose. Kidney failure does not require a dosage correction while liver failure requires usage of other beta-adrenoblockers which are not destructed in liver.


Avoid drinking alcohol as its interaction with Toprol increases drowsiness and dizziness.


Hypersensitivity to the components of the medication, acute or chronic heart failure, arterial hypotention, congestive heart failure, asthma or other breathing problems, diabetes, disorders of peripheral blood circulation, pregnancy, breast-feeding, depression, liver or kidney disease, a thyroid disorder, or myasthenia gravis.

Possible side effect

At the background of common tolerance to the medication among side effects are noticed abdominal cramps, fatigue, insomnia, nausea, depression, memory loss, fever, impotence, lightheadedness, slow heart rate, low blood pressure, cold extremities, sore throat, diarrhea, constipation, and shortness of breath or wheezing.

Drug interaction

Attention should be paid to intake of calcium channel blockers and digoxin (Lanoxin) which are known by dangerous lowering of blood pressure and heart rate being administered together with Toprol.

Toprol also is able to mask the early symptoms of low blood sugar and should be used with caution in patients suffering from diabetes.

Missed dose

Take the forgotten dose when you remember. If your next dose is less than 4 hours away, skip it and return to your schedule. Do not try to compensate a missed dose by taking an extra one.


In case such symptoms of Toprol are noticed: uneven heartbeats, shortness of breath, dizziness, weakness or fainting, bluish-colored fingernails, seek for immediate medical help.


Store between 15-30 C (59-86 F). Protect this drug from moisture and dispensed in tight, keep in a light-resistant container.


We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Antibiotics is one of most prescribed group of medications. Antibiotics are antibacterial (antimicrobial agents) that kills bacteria(bactericidal) or stop the growth of the bacteria(bacteriostatic action).

Antibiotics are used to treat bacterial infections and are not indicated for the viral infections. Currently there is a big variety of antibiotics available. All the antibiotics are divided into two main groups according to the action mechanism:

  • Antibiotics with bactericidal action(penicillins, cephalosporins, aminoglycoside)
  • Antibacterial with bacteriostatic action(macrolides, tetracyclines)

Penicillins and cephalospororins are the most prescribed group of antibiotics. They belong to half-synthetic beta lactam antibiotics. These antibiotics work by inhibiting the enzymes responsible for the production of peptidoglycan. Peptidoglycan is a biopolimer that is a main structural component of the bacterial cell wall. The blockage of peptidoglycan synthesis leads to the lysis of the microorganisms.

Another group of preparations are aminoglycosides. However, these antibiotics are prescribed in rare cases. The most of aminoglycosides possesses nephrotoxicity, ototoxicity and cab cause neuromuscular blockage. Bactericidal action of aminoglycosides is related to the interfering with the synthesis of proteins on the ribisomes in the microbial cells. When aminoglycosides are used with penicillins and cephalosporins the sinergism against gram-positive and gram-negative microorganisms is observed.

Among all bacteriostatic antibiotics macrolides and tetracyclines are the most indicated groups. Therapeutic effect of macrolides is associated with inhibiting the synthesis of proteins on the ribosomes in the microbial cell. As usual macrolides exert bacteriostatic action, however in high amounts are able to exert bactericidal action on some microorganisms. Besides antibacterial action, some macrolides possesses immunomodulatory and anti-inflammatory action.

Another group of bacteriostatic antibiotics are used less frequently as many microorganisms became resistant to the this type of antibiotics. Bacteriostatic effect of the tetracyclines is associated with inhibiting the synthesis of proteins. Tetracycline are indicated in clamydia infections, rickettsial disease, some zoonosis, severe acne.

Antibiotics are indicated and used only in the cases of the bacteria is sensitive to the antibiotics. There some specific tests like antibiogram that will help to determine the right antibiotic and corresponding dose.