Generic Zebeta (Bisoprolol)
Zebeta is a beta-blocker, indicated to treat high blood pressure employed alone or in combination with other antihypertensive drugs.
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Product Description
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Common use

Generic Zebeta contains active ingredient Bisoprolol Fumarate and belongs to a class of drugs called beta-adrenergic receptor blocking agents. Mechanism of its action is to prevent the chemicals transmitting nervous signal between nerves such as norepinephrine and adrenaline to bind receptors on nerves. This way heart rate and blood pressure are reduced as force of heart contractions and tone of blood vessels diminish.

Dosage and direction

Take exactly was it was prescribed by your doctor, do not change your dose and stop taking the rug suddenly as it may worsen your condition.


This medication influences ability to concentration of attention so be specially careful if you need to drive or do work which requires a fast reaction. Before taking Zebeta inform you doctor if you diabetes, psoriasis, predisposed to spasms of bronchi (asthmatic bronchitis, asthma, emphysema) or plan to be operated.


Hypersensitivity, cardiogenic shock, atrioventricular block (degree II and III), sick sinus syndrome, bradicardia (heart rate less than 50 per minute), severe hypotension, disorders of peripheral blood flow in patients who are treated with MAO inhibitors, in patients with chronic heart failure (heart rate less than 60 per minute) pregnancy, breastfeeding, children younger than 12 y.o.

Possible side effect

Side effects are generally transient as Zebeta is well tolerated. If you experience serious symptoms of confusion, hallucinations, nausea, impotence, slow heart rate, low blood pressure, numbness, tingling, cold extremities, pain or burning when you urinate, sore throat, and shortness of breath or wheezing, cramps, diarrhea, dizziness, fatigue, depression, headache, seek for immediate medical attention.

Drug interaction

Rifampin is able to diminish effects of Zebeta as it facilitates its metabolism. Ca+ channel blockes and digoxin can enhance effect of Zebeta which may cause extremely low rate of the heart. Zebeta should be administered two weeks after treatment with MAO inhibitors was discontinued.

Missed dose

If you missed a dose take it as soon as you remember, but do not if it is 4 hours only till the next intake by your schedule. If so skip the missed dose. Do not try to compensate a missed dose by taking an extra one.


If you suspect that you took too much of Zebeta and experience slow heart rate, wheezing or shortness of breath, dizziness, anxiety, confusion, nausea, sweating, pale skin, fainting, and seizure seek for immediate medical attention.


The medication should be stored at room temperature 15-30 C (59-86 F) in a light- resistant box.


We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

Antibiotics is one of most prescribed group of medications. Antibiotics are antibacterial (antimicrobial agents) that kills bacteria(bactericidal) or stop the growth of the bacteria(bacteriostatic action).

Antibiotics are used to treat bacterial infections and are not indicated for the viral infections. Currently there is a big variety of antibiotics available. All the antibiotics are divided into two main groups according to the action mechanism:

  • Antibiotics with bactericidal action(penicillins, cephalosporins, aminoglycoside)
  • Antibacterial with bacteriostatic action(macrolides, tetracyclines)

Penicillins and cephalospororins are the most prescribed group of antibiotics. They belong to half-synthetic beta lactam antibiotics. These antibiotics work by inhibiting the enzymes responsible for the production of peptidoglycan. Peptidoglycan is a biopolimer that is a main structural component of the bacterial cell wall. The blockage of peptidoglycan synthesis leads to the lysis of the microorganisms.

Another group of preparations are aminoglycosides. However, these antibiotics are prescribed in rare cases. The most of aminoglycosides possesses nephrotoxicity, ototoxicity and cab cause neuromuscular blockage. Bactericidal action of aminoglycosides is related to the interfering with the synthesis of proteins on the ribisomes in the microbial cells. When aminoglycosides are used with penicillins and cephalosporins the sinergism against gram-positive and gram-negative microorganisms is observed.

Among all bacteriostatic antibiotics macrolides and tetracyclines are the most indicated groups. Therapeutic effect of macrolides is associated with inhibiting the synthesis of proteins on the ribosomes in the microbial cell. As usual macrolides exert bacteriostatic action, however in high amounts are able to exert bactericidal action on some microorganisms. Besides antibacterial action, some macrolides possesses immunomodulatory and anti-inflammatory action.

Another group of bacteriostatic antibiotics are used less frequently as many microorganisms became resistant to the this type of antibiotics. Bacteriostatic effect of the tetracyclines is associated with inhibiting the synthesis of proteins. Tetracycline are indicated in clamydia infections, rickettsial disease, some zoonosis, severe acne.

Antibiotics are indicated and used only in the cases of the bacteria is sensitive to the antibiotics. There some specific tests like antibiogram that will help to determine the right antibiotic and corresponding dose.